Chronic Nonbacterial Osteomyelitis

Chronic nonbacterial osteomyelitis, or its most severe form, chronic recurrent multifocal is an autoinflammatory bone disease that causes skeletal inflammation characterized by pain and swelling primarily affects children. It a diagnosis of exclusion clinical presentation may mimic underlying infectious processes malignancy. Clinical suspicion for this timely referral to pediatric rheumatology crucial achieve earlier diagnosis, appropriate treatment, improved quality life affected patients families. This article focuses on recent insights into the pathogenesis osteomyelitis outlines advances ongoing research.